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Sustained Hox5 Gene Activity is Required for Respiratory Motor Neuron Development

Respiration in mammals relies on the rhythmic firing of neurons within the Phrenic Motor Column (PMC), a motor neuron group that provides the sole source of diaphragm innervation. Despite their essential role in breathing, the specific determinants of PMC identity and patterns of connectivity are la...

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Detalles Bibliográficos
Autores principales: Philippidou, Polyxeni, Walsh, Carolyn, Aubin, Josée, Jeannotte, Lucie, Dasen, Jeremy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676175/
https://www.ncbi.nlm.nih.gov/pubmed/23103965
http://dx.doi.org/10.1038/nn.3242