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Concurrent Activation of Liver X Receptor and Peroxisome Proliferator-Activated Receptor Alpha Exacerbates Hepatic Steatosis in High Fat Diet-Induced Obese Mice

Liver X receptor (LXR) activation improves glucose homeostasis in obesity. This improvement, however, is associated with several side effects including hyperlipidemia and hepatic steatosis. Activation of peroxisome proliferator-activated receptor alpha (PPARα), on the other hand, increases fatty aci...

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Detalles Bibliográficos
Autores principales: Gao, Mingming, Bu, Le, Ma, Yongjie, Liu, Dexi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676322/
https://www.ncbi.nlm.nih.gov/pubmed/23762402
http://dx.doi.org/10.1371/journal.pone.0065641