R-Loop Mediated Transcription-Associated Recombination in trf4Δ Mutants Reveals New Links between RNA Surveillance and Genome Integrity

To get further insight into the factors involved in the maintenance of genome integrity we performed a screening of Saccharomyces cerevisiae deletion strains inducing hyperrecombination. We have identified trf4, a gene encoding a non-canonical polyA-polymerase involved in RNA surveillance, as a fact...

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Detalles Bibliográficos
Autores principales: Gavaldá, Sandra, Gallardo, Mercedes, Luna, Rosa, Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676323/
https://www.ncbi.nlm.nih.gov/pubmed/23762389
http://dx.doi.org/10.1371/journal.pone.0065541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676323/
https://www.ncbi.nlm.nih.gov/pubmed/23762389
http://dx.doi.org/10.1371/journal.pone.0065541

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