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R-Loop Mediated Transcription-Associated Recombination in trf4Δ Mutants Reveals New Links between RNA Surveillance and Genome Integrity
To get further insight into the factors involved in the maintenance of genome integrity we performed a screening of Saccharomyces cerevisiae deletion strains inducing hyperrecombination. We have identified trf4, a gene encoding a non-canonical polyA-polymerase involved in RNA surveillance, as a fact...
Autores principales: | Gavaldá, Sandra, Gallardo, Mercedes, Luna, Rosa, Aguilera, Andrés |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676323/ https://www.ncbi.nlm.nih.gov/pubmed/23762389 http://dx.doi.org/10.1371/journal.pone.0065541 |
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