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An RGD-Modified MRI-Visible Polymeric Vector for Targeted siRNA Delivery to Hepatocellular Carcinoma in Nude Mice

RNA interference (RNAi) has significant therapeutic promise for the genetic treatment of hepatocellular carcinoma (HCC). Targeted vectors are able to deliver small interfering RNA (siRNA) into HCC cells with high transfection efficiency and stability. The tripeptide arginine glycine aspartic acid (R...

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Detalles Bibliográficos
Autores principales: Wu, Chun, Gong, Faming, Pang, Pengfei, Shen, Min, Zhu, Kangshun, Cheng, Du, Liu, Zhihao, Shan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676333/
https://www.ncbi.nlm.nih.gov/pubmed/23922634
http://dx.doi.org/10.1371/journal.pone.0066416