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Targeting Poly (ADP-Ribose) Polymerase Partially Contributes to Bufalin-Induced Cell Death in Multiple Myeloma Cells

Despite recent pharmaceutical advancements in therapeutic drugs, multiple myeloma (MM) remains an incurable disease. Recently, ploy(ADP-ribose) polymerase 1 (PARP1) has been shown as a potentially promising target for MM therapy. A previous report suggested bufalin, a component of traditional Chines...

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Detalles Bibliográficos
Autores principales: Huang, He, Cao, Yang, Wei, Wei, Liu, Wei, Lu, Shao-Yong, Chen, Yu-Bao, Wang, Yan, Yan, Hua, Wu, Ying-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676346/
https://www.ncbi.nlm.nih.gov/pubmed/23762475
http://dx.doi.org/10.1371/journal.pone.0066130