Differential Regulation of Extracellular Matrix and Soluble Fibulin-1 Levels by TGF-β(1) in Airway Smooth Muscle Cells

Fibulin-1 (FBLN-1) is a secreted glycoprotein that is associated with extracellular matrix (ECM) formation and rebuilding. Abnormal and exaggerated deposition of ECM proteins is a hallmark of many fibrotic diseases, such as chronic obstructive pulmonary disease (COPD) where small airway fibrosis occ...

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Detalles Bibliográficos
Autores principales: Chen, Ling, Ge, Qi, Black, Judith L., Deng, Linhong, Burgess, Janette K., Oliver, Brian G. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676355/
https://www.ncbi.nlm.nih.gov/pubmed/23762390
http://dx.doi.org/10.1371/journal.pone.0065544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676355/
https://www.ncbi.nlm.nih.gov/pubmed/23762390
http://dx.doi.org/10.1371/journal.pone.0065544

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