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nfxB as a Novel Target for Analysis of Mutation Spectra in Pseudomonas aeruginosa

nfxB encodes a negative regulator of the mexCD-oprJ genes for drug efflux in the opportunistic pathogen Pseudomonas aeruginosa. Inactivating mutations in this transcriptional regulator constitute one of the main mechanisms of resistance to ciprofloxacin (Cip(r)). In this work, we evaluated the use o...

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Detalles Bibliográficos
Autores principales: Monti, Mariela R., Morero, Natalia R., Miguel, Virginia, Argaraña, Carlos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676378/
https://www.ncbi.nlm.nih.gov/pubmed/23762483
http://dx.doi.org/10.1371/journal.pone.0066236