Homology Modeling of Human γ-Butyric Acid Transporters and the Binding of Pro-Drugs 5-Aminolevulinic Acid and Methyl Aminolevulinic Acid Used in Photodynamic Therapy

Photodynamic therapy (PDT) is a safe and effective method currently used in the treatment of skin cancer. In ALA-based PDT, 5-aminolevulinic acid (ALA), or ALA esters, are used as pro-drugs to induce the formation of the potent photosensitizer protoporphyrin IX (PpIX). Activation of PpIX by light ca...

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Detalles Bibliográficos
Autores principales: Baglo, Yan, Gabrielsen, Mari, Sylte, Ingebrigt, Gederaas, Odrun A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676387/
https://www.ncbi.nlm.nih.gov/pubmed/23762315
http://dx.doi.org/10.1371/journal.pone.0065200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676387/
https://www.ncbi.nlm.nih.gov/pubmed/23762315
http://dx.doi.org/10.1371/journal.pone.0065200

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