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Antigen Experience Shapes Phenotype and Function of Memory Th1 Cells

Primary and secondary (boosted) memory CD8 T cells exhibit differences in gene expression, phenotype and function. The impact of repeated antigen stimulations on memory CD4 T cells is largely unknown. To address this issue, we utilized LCMV and Listeria monocytogenes infection of mice to characteriz...

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Detalles Bibliográficos
Autores principales: Khanolkar, Aaruni, Williams, Matthew A., Harty, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676405/
https://www.ncbi.nlm.nih.gov/pubmed/23762323
http://dx.doi.org/10.1371/journal.pone.0065234