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Intranasal Immunization of Baculovirus Displayed Hemagglutinin Confers Complete Protection against Mouse Adapted Highly Pathogenic H7N7 Reassortant Influenza Virus

BACKGROUND: Avian influenza A H7N7 virus poses a pandemic threat to human health because of its ability for direct transmission from domestic poultry to humans and from human to human. The wide zoonotic potential of H7N7 combined with an antiviral immunity inhibition similar to pandemic 1918 H1N1 an...

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Detalles Bibliográficos
Autores principales: Rajesh Kumar, Subaschandrabose, Syed Khader, Syed Musthaq, Kiener, Tanja K., Szyporta, Milene, Kwang, Jimmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676417/
https://www.ncbi.nlm.nih.gov/pubmed/23762234
http://dx.doi.org/10.1371/journal.pone.0063856