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Case-Control Association Testing of Common Variants from Sequencing of DNA Pools

While genome-wide association studies (GWAS) have been successful in identifying a large number of variants associated with disease, the challenge of locating the underlying causal loci remains. Sequencing of case and control DNA pools provides an inexpensive method for assessing all variation in a...

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Detalles Bibliográficos
Autores principales: McRae, Allan F., Richter, Melinda M., Lind, Penelope A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676437/
https://www.ncbi.nlm.nih.gov/pubmed/23762362
http://dx.doi.org/10.1371/journal.pone.0065410