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Case-Control Association Testing of Common Variants from Sequencing of DNA Pools
While genome-wide association studies (GWAS) have been successful in identifying a large number of variants associated with disease, the challenge of locating the underlying causal loci remains. Sequencing of case and control DNA pools provides an inexpensive method for assessing all variation in a...
Autores principales: | McRae, Allan F., Richter, Melinda M., Lind, Penelope A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676437/ https://www.ncbi.nlm.nih.gov/pubmed/23762362 http://dx.doi.org/10.1371/journal.pone.0065410 |
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