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Hepatitis C Virus Infection Activates a Novel Innate Pathway Involving IKKα in Lipogenesis and Viral Assembly

Hepatitis C virus interacts extensively with host factors not only to establish productive infection but also to trigger unique pathological processes. Our recent genome-wide siRNA screen demonstrated that IKKα is a critical host factor for HCV. Here we describe a novel NF-κB-independent and kinase-...

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Detalles Bibliográficos
Autores principales: Li, Qisheng, Pène, Véronique, Krishnamurthy, Siddharth, Cha, Helen, Liang, T. Jake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676727/
https://www.ncbi.nlm.nih.gov/pubmed/23708292
http://dx.doi.org/10.1038/nm.3190