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Hepatitis C Virus Infection Activates a Novel Innate Pathway Involving IKKα in Lipogenesis and Viral Assembly
Hepatitis C virus interacts extensively with host factors not only to establish productive infection but also to trigger unique pathological processes. Our recent genome-wide siRNA screen demonstrated that IKKα is a critical host factor for HCV. Here we describe a novel NF-κB-independent and kinase-...
Autores principales: | Li, Qisheng, Pène, Véronique, Krishnamurthy, Siddharth, Cha, Helen, Liang, T. Jake |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676727/ https://www.ncbi.nlm.nih.gov/pubmed/23708292 http://dx.doi.org/10.1038/nm.3190 |
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