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hTERT promoter polymorphism, -1327C>T, is associated with the risk of epithelial cancer

Telomeres are repetitive nucleotide sequences that cap the end of eukaryotic chromosomes. Attrition of these structures has been associated with carcinogenesis in many tissues, and therefore, they are essential for chromosome stabilization. Telomeres are maintained by telomerase complexes, of which...

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Detalles Bibliográficos
Autores principales: Iizuka, Toshihiko, Sawabe, Motoji, Takubo, Kaiyo, Liu, Miao, Homma, Yukio, Suzuki, Motofumi, Arai, Tomio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676739/
https://www.ncbi.nlm.nih.gov/pubmed/23762817
http://dx.doi.org/10.1186/2193-1801-2-249