Analysis of 6,515 exomes reveals a recent origin of most human protein-coding variants

Establishing the age of each mutation segregating in contemporary human populations is important to fully understand our evolutionary history(1,2) and will help facilitate the development of new approaches for disease gene discovery(3). Large-scale surveys of human genetic variation have reported si...

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Detalles Bibliográficos
Autores principales: Fu, Wenqing, O'Connor, Timothy D., Jun, Goo, Kang, Hyun Min, Abecasis, Goncalo, Leal, Suzanne M., Gabriel, Stacey, Altshuler, David, Shendure, Jay, Nickerson, Deborah A., Bamshad, Michael J., GO, Broad, GO, Seattle, Akey, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676746/
https://www.ncbi.nlm.nih.gov/pubmed/23201682
http://dx.doi.org/10.1038/nature11690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676746/
https://www.ncbi.nlm.nih.gov/pubmed/23201682
http://dx.doi.org/10.1038/nature11690

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