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Two Distinct Channels Mediated by m2mAChR and α9nAChR Co-Exist in Type II Vestibular Hair Cells of Guinea Pig

Acetylcholine (ACh) is the principal vestibular efferent neurotransmitter among mammalians. Pharmacologic studies prove that ACh activates a small conductance Ca(2+)-activated K(+) channels (KCa) current (SK2), mediated by α9-containing nicotinic ACh receptor (α9nAChR) in mammalian type II vestibula...

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Detalles Bibliográficos
Autores principales: Zhou, Tao, Wang, Yi, Guo, Chang-Kai, Zhang, Wen-Juan, Yu, Hong, Zhang, Kun, Kong, Wei-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676758/
https://www.ncbi.nlm.nih.gov/pubmed/23615472
http://dx.doi.org/10.3390/ijms14058818