Off-Target Effect of Endogenous siRNA Derived from RMRP in Human Cells

Endogenous siRNAs (endo-siRNAs) are key regulators of RNA silencing in plants and worms; however, the biogenesis and function of endogenous siRNAs in mammals remain largely unknown. We previously demonstrated that human telomerase reverse transcriptase produces a self-targeting endogenous siRNA from...

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Detalles Bibliográficos
Autores principales: Maida, Yoshiko, Kyo, Satoru, Lassmann, Timo, Hayashizaki, Yoshihide, Masutomi, Kenkichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676784/
https://www.ncbi.nlm.nih.gov/pubmed/23629666
http://dx.doi.org/10.3390/ijms14059305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676784/
https://www.ncbi.nlm.nih.gov/pubmed/23629666
http://dx.doi.org/10.3390/ijms14059305

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