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D-pinitol Inhibits Prostate Cancer Metastasis through Inhibition of αVβ3 Integrin by Modulating FAK, c-Src and NF-κB Pathways

Prostate cancer is the most commonly diagnosed malignancy in men and shows a predilection for metastasis to the bone. D-pinitol, a 3-methoxy analogue of d-chiro-inositol, was identified as an active principle in soy foods and legumes, and it has been proven to induce tumor apoptosis and metastasis o...

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Detalles Bibliográficos
Autores principales: Lin, Tien-Huang, Tan, Tzu-Wei, Tsai, Tsung-Hsun, Chen, Chi-Cheng, Hsieh, Teng-Fu, Lee, Shang-Sen, Liu, Hsin-Ho, Chen, Wen-Chi, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676813/
https://www.ncbi.nlm.nih.gov/pubmed/23698767
http://dx.doi.org/10.3390/ijms14059790