Ultraviolet (UV) and Hydrogen Peroxide Activate Ceramide-ER Stress-AMPK Signaling Axis to Promote Retinal Pigment Epithelium (RPE) Cell Apoptosis

Ultraviolet (UV) radiation and reactive oxygen species (ROS) impair the physiological functions of retinal pigment epithelium (RPE) cells by inducing cell apoptosis, which is the main cause of age-related macular degeneration (AMD). The mechanism by which UV/ROS induces RPE cell death is not fully a...

Descripción completa

Detalles Bibliográficos
Autores principales: Yao, Jin, Bi, Hui-E, Sheng, Yi, Cheng, Li-Bo, Wendu, Ri-Le, Wang, Cheng-Hu, Cao, Guo-Fan, Jiang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676843/
https://www.ncbi.nlm.nih.gov/pubmed/23685869
http://dx.doi.org/10.3390/ijms140510355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676843/
https://www.ncbi.nlm.nih.gov/pubmed/23685869
http://dx.doi.org/10.3390/ijms140510355

Ejemplares similares