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Human Prostatic Acid Phosphatase: Structure, Function and Regulation

Human prostatic acid phosphatase (PAcP) is a 100 kDa glycoprotein composed of two subunits. Recent advances demonstrate that cellular PAcP (cPAcP) functions as a protein tyrosine phosphatase by dephosphorylating ErbB-2/Neu/HER-2 at the phosphotyrosine residues in prostate cancer (PCa) cells, which r...

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Detalles Bibliográficos
Autores principales: Muniyan, Sakthivel, Chaturvedi, Nagendra K., Dwyer, Jennifer G., LaGrange, Chad A., Chaney, William G., Lin, Ming-Fong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676848/
https://www.ncbi.nlm.nih.gov/pubmed/23698773
http://dx.doi.org/10.3390/ijms140510438