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Inhibition of CCL2 Signaling in Combination with Docetaxel Treatment Has Profound Inhibitory Effects on Prostate Cancer Growth in Bone

The C-C chemokine ligand 2 (CCL2) stimulates migration, proliferation, and invasion of prostate cancer (PCa) cells, and its signaling also plays a role in the activation of osteoclasts. Therefore targeting CCL2 signaling in regulation of tumor progression in bone metastases is an area of intense res...

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Detalles Bibliográficos
Autores principales: Kirk, Peter S., Koreckij, Theodore, Nguyen, Holly M., Brown, Lisha G., Snyder, Linda A., Vessella, Robert L., Corey, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676850/
https://www.ncbi.nlm.nih.gov/pubmed/23698775
http://dx.doi.org/10.3390/ijms140510483