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What Renders TAU Toxic

TAU is a microtubule-associated protein that under pathological conditions such as Alzheimer’s disease (AD) forms insoluble, filamentous aggregates. When 20 years after TAU’s discovery the first TAU transgenic mouse models were established, one declared goal that was achieved was the modeling of aut...

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Detalles Bibliográficos
Autores principales: Götz, Jürgen, Xia, Di, Leinenga, Gerhard, Chew, Yee Lian, Nicholas, Hannah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677143/
https://www.ncbi.nlm.nih.gov/pubmed/23772223
http://dx.doi.org/10.3389/fneur.2013.00072