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What Renders TAU Toxic
TAU is a microtubule-associated protein that under pathological conditions such as Alzheimer’s disease (AD) forms insoluble, filamentous aggregates. When 20 years after TAU’s discovery the first TAU transgenic mouse models were established, one declared goal that was achieved was the modeling of aut...
Autores principales: | Götz, Jürgen, Xia, Di, Leinenga, Gerhard, Chew, Yee Lian, Nicholas, Hannah R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677143/ https://www.ncbi.nlm.nih.gov/pubmed/23772223 http://dx.doi.org/10.3389/fneur.2013.00072 |
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