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The Tumor Microenvironment and Strategies to Improve Drug Distribution

The microenvironment within tumors is composed of a heterogeneous mixture of cells with varying levels of nutrients and oxygen. Differences in oxygen content result in survival or compensatory mechanisms within tumors that may favor a more malignant or lethal phenotype. Cells that are rapidly prolif...

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Detalles Bibliográficos
Autores principales: Saggar, Jasdeep K., Yu, Man, Tan, Qian, Tannock, Ian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677151/
https://www.ncbi.nlm.nih.gov/pubmed/23772420
http://dx.doi.org/10.3389/fonc.2013.00154