Global Mapping of Transcription Factor Binding Sites by Sequencing Chromatin Surrogates: a Perspective on Experimental Design, Data Analysis, and Open Problems

Mapping genome-wide binding sites of all transcription factors (TFs) in all biological contexts is a critical step toward understanding gene regulation. The state-of-the-art technologies for mapping transcription factor binding sites (TFBSs) couple chromatin immunoprecipitation (ChIP) with high-thro...

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Detalles Bibliográficos
Autores principales: Wei, Yingying, Wu, George, Ji, Hongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677239/
https://www.ncbi.nlm.nih.gov/pubmed/23762209
http://dx.doi.org/10.1007/s12561-012-9066-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677239/
https://www.ncbi.nlm.nih.gov/pubmed/23762209
http://dx.doi.org/10.1007/s12561-012-9066-5

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