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Microtubule dynamic instability: A new model with coupled GTP hydrolysis and multistep catastrophe

A key question in understanding microtubule dynamics is how GTP hydrolysis leads to catastrophe, the switch from slow growth to rapid shrinkage. We first provide a review of the experimental and modeling literature, and then present a new model of microtubule dynamics. We demonstrate that vectorial,...

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Detalles Bibliográficos
Autores principales: Bowne-Anderson, Hugo, Zanic, Marija, Kauer, Monika, Howard, Jonathon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677417/
https://www.ncbi.nlm.nih.gov/pubmed/23532586
http://dx.doi.org/10.1002/bies.201200131