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Microtubule dynamic instability: A new model with coupled GTP hydrolysis and multistep catastrophe
A key question in understanding microtubule dynamics is how GTP hydrolysis leads to catastrophe, the switch from slow growth to rapid shrinkage. We first provide a review of the experimental and modeling literature, and then present a new model of microtubule dynamics. We demonstrate that vectorial,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677417/ https://www.ncbi.nlm.nih.gov/pubmed/23532586 http://dx.doi.org/10.1002/bies.201200131 |