Interaction of Human Dopa Decarboxylase with L-Dopa: Spectroscopic and Kinetic Studies as a Function of pH

Human Dopa decarboxylase (hDDC), a pyridoxal 5′-phosphate (PLP) enzyme, displays maxima at 420 and 335 nm and emits fluorescence at 384 and 504 nm upon excitation at 335 nm and at 504 nm when excited at 420 nm. Absorbance and fluorescence titrations of hDDC-bound coenzyme identify a single pK(spec)...

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Detalles Bibliográficos
Autores principales: Montioli, Riccardo, Cellini, Barbara, Dindo, Mirco, Oppici, Elisa, Voltattorni, Carla Borri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677616/
https://www.ncbi.nlm.nih.gov/pubmed/23781496
http://dx.doi.org/10.1155/2013/161456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677616/
https://www.ncbi.nlm.nih.gov/pubmed/23781496
http://dx.doi.org/10.1155/2013/161456

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