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TET2 Mutations in Ph-Negative Myeloproliferative Neoplasms: Identification of Three Novel Mutations and Relationship with Clinical and Laboratory Findings

High-throughput DNA sequence analysis was used to screen for TET2 mutations in peripheral blood derived DNA from 97 patients with BCR-ABL-negative myeloproliferative neoplasms (MPNs). Overall six mutations in the coding region of the gene were identified in 7 patients with an overall mutational freq...

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Detalles Bibliográficos
Autores principales: Patriarca, Andrea, Colaizzo, Donatella, Tiscia, Gianluca, Spadano, Raffaele, Di Zacomo, Silvia, Spadano, Antonio, Villanova, Ida, Margaglione, Maurizio, Grandone, Elvira, Dragani, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677649/
https://www.ncbi.nlm.nih.gov/pubmed/23781511
http://dx.doi.org/10.1155/2013/929840