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Empirical pathway analysis, without permutation

Resampling-based expression pathway analysis techniques have been shown to preserve type I error rates, in contrast to simple gene-list approaches that implicitly assume the independence of genes in ranked lists. However, resampling is intensive in computation time and memory requirements. We descri...

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Detalles Bibliográficos
Autores principales: Zhou, Yi-Hui, Barry, William T., Wright, Fred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677738/
https://www.ncbi.nlm.nih.gov/pubmed/23428933
http://dx.doi.org/10.1093/biostatistics/kxt004