Prenatal Endotoxemia and Placental Drug Transport in The Mouse: Placental Size-Specific Effects

Lipopolysaccharide (LPS) in high doses inhibits placental multidrug resistance P-glycoprotein (P-gp - Abcb1a/b) and breast cancer resistance protein (BCRP - Abcg2). This potentially impairs fetal protection against harmful factors in the maternal circulation. However, it is unknown whether LPS expos...

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Detalles Bibliográficos
Autores principales: Bloise, Enrrico, Bhuiyan, Manzerul, Audette, Melanie C., Petropoulos, Sophie, Javam, Mohsen, Gibb, William, Matthews, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677882/
https://www.ncbi.nlm.nih.gov/pubmed/23762418
http://dx.doi.org/10.1371/journal.pone.0065728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677882/
https://www.ncbi.nlm.nih.gov/pubmed/23762418
http://dx.doi.org/10.1371/journal.pone.0065728

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