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Prenatal Endotoxemia and Placental Drug Transport in The Mouse: Placental Size-Specific Effects
Lipopolysaccharide (LPS) in high doses inhibits placental multidrug resistance P-glycoprotein (P-gp - Abcb1a/b) and breast cancer resistance protein (BCRP - Abcg2). This potentially impairs fetal protection against harmful factors in the maternal circulation. However, it is unknown whether LPS expos...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677882/ https://www.ncbi.nlm.nih.gov/pubmed/23762418 http://dx.doi.org/10.1371/journal.pone.0065728 |