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Self-Oligomerization Is Essential for Enhanced Immunological Activities of Soluble Recombinant Calreticulin

We have recently reported that calreticulin (CRT), a luminal resident protein, can be found in the sera of patients with rheumatoid arthritis and also that recombinant CRT (rCRT) exhibits extraordinarily strong immunological activities. We herein further demonstrate that rCRT fragments 18–412 (rCRT/...

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Detalles Bibliográficos
Autores principales: Huang, Shang-Hui, Zhao, Li-Xiang, Hong, Chao, Duo, Cui-Cui, Guo, Bing-Nan, Zhang, Li-Juan, Gong, Zheng, Xiong, Si-Dong, Gong, Fang-Yuan, Gao, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677884/
https://www.ncbi.nlm.nih.gov/pubmed/23762269
http://dx.doi.org/10.1371/journal.pone.0064951