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Self-Oligomerization Is Essential for Enhanced Immunological Activities of Soluble Recombinant Calreticulin
We have recently reported that calreticulin (CRT), a luminal resident protein, can be found in the sera of patients with rheumatoid arthritis and also that recombinant CRT (rCRT) exhibits extraordinarily strong immunological activities. We herein further demonstrate that rCRT fragments 18–412 (rCRT/...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677884/ https://www.ncbi.nlm.nih.gov/pubmed/23762269 http://dx.doi.org/10.1371/journal.pone.0064951 |