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Biochemical and Functional Analysis of Drosophila-Sciara Chimeric Sex-Lethal Proteins

BACKGROUND: The Drosophila SXL protein controls sex determination and dosage compensation. It is a sex-specific factor controlling splicing of its own Sxl pre-mRNA (auto-regulation), tra pre-mRNA (sex determination) and msl-2 pre-mRNA plus translation of msl-2 mRNA (dosage compensation). Outside the...

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Detalles Bibliográficos
Autores principales: Ruiz, María Fernanda, Sarno, Francesca, Zorrilla, Silvia, Rivas, Germán, Sánchez, Lucas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677924/
https://www.ncbi.nlm.nih.gov/pubmed/23762307
http://dx.doi.org/10.1371/journal.pone.0065171