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Real Time Measures of Prestin Charge and Fluorescence during Plasma Membrane Trafficking Reveal Sub-Tetrameric Activity

Prestin (SLC26a5) is the outer hair cell integral membrane motor protein that drives cochlear amplification, and has been described as an obligate tetramer. We studied in real time the delivery of YFP-prestin to the plasma membrane of cells from a tetracycline-inducible cell line. Following the rele...

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Detalles Bibliográficos
Autores principales: Bian, Shumin, Navaratnam, Dhasakumar, Santos-Sacchi, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677934/
https://www.ncbi.nlm.nih.gov/pubmed/23762468
http://dx.doi.org/10.1371/journal.pone.0066078