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The ryanodine receptor leak: how a tattered receptor plunges the failing heart into crisis
It has been persuasively shown in the last two decades that the development of heart failure is closely linked to distinct alterations in Ca(2+) cycling. A crucial point in this respect is an increased spontaneous release of Ca(2+) out of the sarcoplasmic reticulum during diastole via ryanodine rece...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677980/ https://www.ncbi.nlm.nih.gov/pubmed/22932727 http://dx.doi.org/10.1007/s10741-012-9339-6 |