Cargando…
Thermostabilisation of the Serotonin Transporter in a Cocaine-Bound Conformation
Structure determination of mammalian integral membrane proteins is challenging due to their instability upon detergent solubilisation and purification. Recent successes in the structure determination of G-protein-coupled receptors (GPCRs) resulted from the development of GPCR-specific protein engine...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678023/ https://www.ncbi.nlm.nih.gov/pubmed/23706649 http://dx.doi.org/10.1016/j.jmb.2013.03.025 |