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Thermostabilisation of the Serotonin Transporter in a Cocaine-Bound Conformation

Structure determination of mammalian integral membrane proteins is challenging due to their instability upon detergent solubilisation and purification. Recent successes in the structure determination of G-protein-coupled receptors (GPCRs) resulted from the development of GPCR-specific protein engine...

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Detalles Bibliográficos
Autores principales:	Abdul-Hussein, Saba, Andréll, Juni, Tate, Christopher G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678023/ https://www.ncbi.nlm.nih.gov/pubmed/23706649 http://dx.doi.org/10.1016/j.jmb.2013.03.025

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