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Notch Signaling is Associated with ALDH Activity and an Aggressive Metastatic Phenotype in Murine Osteosarcoma Cells

Osteosarcoma (OS) is the most common primary malignancy of bone, and pulmonary metastatic disease accounts for nearly all mortality. However, little is known about the biochemical signaling alterations that drive the progression of metastatic disease. Two murine OS cell populations, K7M2 and K12, ar...

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Detalles Bibliográficos
Autores principales: Mu, Xiaodong, Isaac, Christian, Greco, Nicholas, Huard, Johnny, Weiss, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678113/
https://www.ncbi.nlm.nih.gov/pubmed/23805413
http://dx.doi.org/10.3389/fonc.2013.00143