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The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo

Though critical to normal development and cancer metastasis, how cells traverse basement membranes is poorly understood. A central impediment has been the challenge of visualizing invasive cell interactions with basement membrane in vivo. By developing live-cell imaging methods to follow anchor cell...

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Detalles Bibliográficos
Autores principales: Hagedorn, Elliott J., Ziel, Joshua W., Morrissey, Meghan A., Linden, Lara M., Wang, Zheng, Chi, Qiuyi, Johnson, Sam A., Sherwood, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678161/
https://www.ncbi.nlm.nih.gov/pubmed/23751497
http://dx.doi.org/10.1083/jcb.201301091