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The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo
Though critical to normal development and cancer metastasis, how cells traverse basement membranes is poorly understood. A central impediment has been the challenge of visualizing invasive cell interactions with basement membrane in vivo. By developing live-cell imaging methods to follow anchor cell...
Autores principales: | Hagedorn, Elliott J., Ziel, Joshua W., Morrissey, Meghan A., Linden, Lara M., Wang, Zheng, Chi, Qiuyi, Johnson, Sam A., Sherwood, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678161/ https://www.ncbi.nlm.nih.gov/pubmed/23751497 http://dx.doi.org/10.1083/jcb.201301091 |
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