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Molecular Characterization and Clinical Impact of TMPRSS2-ERG Rearrangement on Prostate Cancer: Comparison between FISH and RT-PCR

Prostate cancer (PCa) is a very heterogeneous disease, and there are constraints in its current diagnosis. Serum PSA levels, digital rectal examination (DRE), and histopathologic analysis often drive to overdiagnosis and overtreatment. Since 2005, the presence of the genetic rearrangement between tr...

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Detalles Bibliográficos
Autores principales: Fernández-Serra, A., Rubio, L., Calatrava, A., Rubio-Briones, J., Salgado, R., Gil-Benso, R., Espinet, B., García-Casado, Z., López-Guerrero, J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678465/
https://www.ncbi.nlm.nih.gov/pubmed/23781502
http://dx.doi.org/10.1155/2013/465179