Coexistence of two different mutations in codon 12 of the Kras gene in colorectal cancer: Report of a case supporting the concept of tumoral heterogeneity

Evaluation of the mutational status of KRAS is a crucial step for the correct therapeutic approach in treating advanced colorectal cancer as the identification of wild-type KRAS tumors leads to more specific and less toxic treatments for patients. Although several studies have highlighted the differ...

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Detalles Bibliográficos
Autores principales: IMPROTA, GIUSEPPINA, ZUPA, ANGELA, POSSIDENTE, LUCIANA, TARTARONE, ALFREDO, PEDICINI, PIERNICOLA, NAPPI, ANTONIO, MOLINARI, SERGIO, FRAGGETTA, FILIPPO, VITA, GIULIA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678636/
https://www.ncbi.nlm.nih.gov/pubmed/23761841
http://dx.doi.org/10.3892/ol.2013.1255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678636/
https://www.ncbi.nlm.nih.gov/pubmed/23761841
http://dx.doi.org/10.3892/ol.2013.1255

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