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Coexistence of two different mutations in codon 12 of the Kras gene in colorectal cancer: Report of a case supporting the concept of tumoral heterogeneity
Evaluation of the mutational status of KRAS is a crucial step for the correct therapeutic approach in treating advanced colorectal cancer as the identification of wild-type KRAS tumors leads to more specific and less toxic treatments for patients. Although several studies have highlighted the differ...
Autores principales: | IMPROTA, GIUSEPPINA, ZUPA, ANGELA, POSSIDENTE, LUCIANA, TARTARONE, ALFREDO, PEDICINI, PIERNICOLA, NAPPI, ANTONIO, MOLINARI, SERGIO, FRAGGETTA, FILIPPO, VITA, GIULIA |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678636/ https://www.ncbi.nlm.nih.gov/pubmed/23761841 http://dx.doi.org/10.3892/ol.2013.1255 |
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