Multiple copies of BCR-ABL fusion gene on two isodicentric Philadelphia chromosomes in an imatinib mesylate-resistant chronic myeloid leukemia patient

The so-called Philadelphia (Ph) chromosome is present in more than 90% of chronic myeloid leukemia (CML) cases. Amplification or duplication of the BCR-ABL gene has been found to be one of the key factors leading to drug resistance to imatinib mesylate (IM). In the present study, we identified the p...

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Detalles Bibliográficos
Autores principales: AL-ACHKAR, WALID, WAFA, ABDULSAMAD, MOASSASS, FATEN, KLEIN, ELISABETH, LIEHR, THOMAS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678658/
https://www.ncbi.nlm.nih.gov/pubmed/23761821
http://dx.doi.org/10.3892/ol.2013.1225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678658/
https://www.ncbi.nlm.nih.gov/pubmed/23761821
http://dx.doi.org/10.3892/ol.2013.1225

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