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Direct alkenylation of indolin-2-ones by 6-aryl-4-methylthio-2H-pyran-2-one-3-carbonitriles: a novel approach

A direct one-pot base-induced alkenylation of indolin-2-ones has been developed by using 6-aryl-4-methylthio-2H-pyran-2-one-3-carbonitriles. Different bases such as MeONa, NaH and t-BuONa have been used to optimize the reaction conditions to obtain the desired product. NaH in THF was found to be the...

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Detalles Bibliográficos
Autores principales: Kumar, Sandeep, Pratap, Ramendra, Kumar, Abhinav, Kumar, Brijesh, Tandon, Vishnu K, Ram, Vishnu Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678717/
https://www.ncbi.nlm.nih.gov/pubmed/23766794
http://dx.doi.org/10.3762/bjoc.9.92