Impact of Heparanase and the Tumor Microenvironment on Cancer Metastasis and Angiogenesis: Basic Aspects and Clinical Applications

Heparanase is an endo-β-D-glucuronidase that cleaves heparan sulfate (HS) side chains at a limited number of sites, activity that is strongly implicated with cell invasion associated with cancer metastasis, a consequence of structural modification that loosens the extracellular matrix barrier. Hepar...

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Detalles Bibliográficos
Autores principales: Vlodavsky, Israel, Elkin, Michael, Ilan, Neta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rambam Health Care Campus 2011
Materias:
Discoveries from the Bench to the Bedside
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678787/
https://www.ncbi.nlm.nih.gov/pubmed/23908791
http://dx.doi.org/10.5041/RMMJ.10019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678787/
https://www.ncbi.nlm.nih.gov/pubmed/23908791
http://dx.doi.org/10.5041/RMMJ.10019

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