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The Contentious History of Sirtuin Debates
The sirtuins are highly conserved enzyme homologues of the yeast Sir2, with activities of NAD+ dependent deacetylase and/or mono ADP ribosyltransferase. A long line of evidence has implicated sirtuins in regulating the aging process of yeast, worms, flies, and rodents. Moreover, much work has been p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rambam Health Care Campus
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678826/ https://www.ncbi.nlm.nih.gov/pubmed/23908846 http://dx.doi.org/10.5041/RMMJ.10093 |