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The Contentious History of Sirtuin Debates

The sirtuins are highly conserved enzyme homologues of the yeast Sir2, with activities of NAD+ dependent deacetylase and/or mono ADP ribosyltransferase. A long line of evidence has implicated sirtuins in regulating the aging process of yeast, worms, flies, and rodents. Moreover, much work has been p...

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Detalles Bibliográficos
Autores principales: Naiman, Shoshana, Cohen, Haim Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rambam Health Care Campus 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678826/
https://www.ncbi.nlm.nih.gov/pubmed/23908846
http://dx.doi.org/10.5041/RMMJ.10093