Low-weight polyethylenimine cross-linked 2-hydroxypopyl-β-cyclodextrin and folic acid as an efficient and nontoxic siRNA carrier for gene silencing and tumor inhibition by VEGF siRNA

BACKGROUND: Targeted delivery of small interfering RNA (siRNA) has been regarded as one of the most important technologies for the development of siRNA therapeutics. However, the need for safe and efficient delivery systems is a barrier to further development of RNA interference therapeutics. In thi...

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Detalles Bibliográficos
Autores principales: Li, Jin-Ming, Wang, Yuan-Yuan, Zhang, Wei, Su, Hua, Ji, Liang-Nian, Mao, Zong-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678862/
https://www.ncbi.nlm.nih.gov/pubmed/23766646
http://dx.doi.org/10.2147/IJN.S42440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678862/
https://www.ncbi.nlm.nih.gov/pubmed/23766646
http://dx.doi.org/10.2147/IJN.S42440

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